PE 22-28 — research peptide based on the spadin sequence. Studied as TREK-1 channel inhibitor.

PE 22-28 is a 7-amino-acid research peptide derived from the spadin sequence. It is studied as a selective inhibitor of TREK-1 (TWIK-related K+ channel 1).
PE 22-28 selectively inhibits TREK-1 — a two-pore-domain potassium channel implicated in mood research. TREK-1 inhibition has been studied for antidepressant-like research effects.
Used in: TREK-1 channel research, mood pathway studies, comparative spadin analog research.
| Compound | PE 22-28 |
| Available Strengths | 10mg |
| Purity | ≥99% (verified by HPLC) |
| Form | Lyophilized powder |
| Storage | -20°C, protected from light |
| Reconstitution | Bacteriostatic water (sold separately) |
| Shelf Life | 36 months (lyophilized, properly stored) |
| Certificate of Analysis | Available upon request — contact us |
Add bacteriostatic water slowly. Use within 28 days.
Lyophilized: -20°C. Reconstituted: 2-8°C.
For research use only. Not for human consumption.